HPV2 E4
Accession: H002786
Protein: E4
Organism: Human papillomavirus type 2
Function
It is responsible for recognition and binding of origin of replication. It exists in two forms such as full length (transcriptional transactivator) and truncated (transcriptional repressor). The ratio of these found in the heterotrimeric complex, formed b
Domain&Motif
| method | domain/motif name | position | length | description | graphical view |
|---|---|---|---|---|---|
| CDD | Pap_E4 | 3505-3618 | 114 | E4 protein; This is is a family of Papillomavirus proteins, E4, coded for by ORF4. A splice variant, E1--E4, exists but neither the function of E4 or E1--E4 is known. | |
| INTERPROSCAN | 3286-3618 | 333 | |||
| MOTIF_SEAR_IN_PROT | 3286-3618 | 333 | |||
| MOTIF_SEAR_IN_PROT | 3469-3612 | 144 | |||
| MOTIF_SEAR_IN_PROT | 3526-3618 | 93 | |||
| MOTIF_SEAR_IN_PROT | 3352-3582 | 231 | |||
| MOTIF_SEAR_IN_PROT | 3295-3459 | 165 | |||
| MOTIF_SEAR_IN_PROT | 3295-3504 | 210 | |||
| MOTIF_SEAR_IN_PROT | 3544-3603 | 60 | |||
| MOTIF_SEAR_IN_PROT | 3433-3591 | 159 | |||
| MOTIF_SEAR_IN_PROT | 3280-3534 | 255 | |||
| MOTIF_SEAR_IN_PROT | 3538-3612 | 75 | |||
| MOTIF_SEAR_IN_PROT | 3334-3585 | 252 | |||
| MOTIF_SEAR_IN_PROT | 3448-3552 | 105 | |||
| MOTIF_SEAR_IN_PROT | 3367-3498 | 132 | |||
| MOTIF_SEAR_IN_PROT | 3301-3585 | 285 | |||
| MOTIF_SEAR_IN_PROT | 3286-3618 | 333 | |||
| PROSITE_SCAN | 3259-3276 | 18 | |||
| PROSITE_SCAN | 3454-3465 | 12 | |||
| PROSITE_SCAN | 3475-3486 | 12 | |||
| PROSITE_SCAN | 3505-3513 | 9 | |||
| PROSITE_SCAN | 3505-3516 | 12 | |||
| PROSITE_SCAN | 3520-3528 | 9 | |||
| PROSITE_SCAN | 3553-3570 | 18 | |||
| PROSITE_SCAN | 3589-3606 | 18 | |||
| SBASE | 3520-3618 | 99 | |||
| TMPRED_SERVER | 3235-3297 | 63 | |||
| TMPRED_SERVER | 3241-3297 | 57 | |||
| TMPRED_SERVER | 3559-3615 | 57 | |||
| TMPRED_SERVER | 3571-3621 | 51 |
Sequence
. . . . . . G:3282
atggggtcaccgggacgtgggaggtgcacgtggctgggactgttattcaccatacatccg C:60
M G S P G R G R C T W L G L L F T I H P P:20
. . . . . . G:3342
catctgtgtctagcacccaggccagcgcctcggacgacgaaccactatcccctattagaa C:60
H L C L A P R P A P R T T N H Y P L L E P:20
. . . . . . G:3402
ctgctgtatccccagtcccagccccagtcgcagcctcagcagaatcaacaggagcaggaa C:60
L L Y P Q S Q P Q S Q P Q Q N Q Q E Q E P:20
. . . . . . G:3462
gagcagctccgcccacccaagcgttgtgctccgcccaggcgccaacgagtccgccggcca C:60
E Q L R P P K R C A P P R R Q R V R R P P:20
. . . . . . G:3522
agcgccagcgtgtcatcgtcggacagcagcatccccggcccgactctacgcgaacggtcg C:60
S A S V S S S D S S I P G P T L R E R S P:20
. . . . . . G:3582
gagagggggaagtggagtgttacaacaagcggagcatcagtgactctaaccgcacagacc C:60
E R G K W S V T T S G A S V T L T A Q T P:20
. . . G:3621
ccaggtggggccacggtgacactgactctgtgcctgtaa C:39
P G G A T V T L T L C L P:12