HPV59 E7
Accession: H000501
NC: ACL12335.1
Uniprot: Q81965
Protein: E7
Organism: Human papillomavirus type 59
Function
E7 protein is transforming protein. It binds to pRB/p107 and promotes its complete degradation.
Domain&Motif
| method | domain/motif name | position | length | description | graphical view |
|---|---|---|---|---|---|
| CDD | E7 | 548-853 | 306 | E7 protein, Early protein; | |
| CDD | PHA02776 | 542-853 | 312 | E7 protein; Provisional | |
| MOTIF_SCAN | 560-571 | 12 | |||
| MOTIF_SCAN | 641-652 | 12 | |||
| MOTIF_SCAN | 779-790 | 12 | |||
| MOTIF_SCAN | 602-667 | 66 | |||
| MOTIF_SCAN | 548-853 | 306 | |||
| MOTIF_SCAN | 548-853 | 306 | |||
| INTERPROSCAN | 548-850 | 303 | |||
| INTERPROSCAN | 542-862 | 321 | |||
| MOTIF_SEAR_IN_PROT | 548-853 | 306 | |||
| MOTIF_SEAR_IN_PROT | 542-853 | 312 | |||
| MOTIF_SEAR_IN_PROT | 602-667 | 66 | |||
| MOTIF_SEAR_IN_PROT | 548-850 | 303 | |||
| MOTIF_SEAR_IN_PROT | 677-781 | 105 | |||
| PROSITE_SCAN | 560-571 | 12 | |||
| PROSITE_SCAN | 641-652 | 12 | |||
| PROSITE_SCAN | 779-790 | 12 | |||
| SBASE | 542-853 | 312 | |||
| TMPRED_SERVER | 836-895 | 60 | |||
| TMPRED_SERVER | 845-895 | 51 |
Sequence
. . . . . . G:601
atggcacgctttgaggatcctacacaacgaccatacaaactgcctgatttgagcacaaca C:60
M H G P K A T L C D I V L D L E P Q N Y P:20
. . . . . . G:661
ttgaatattcctctgcatgatattcgcatcaattgtgtgttttgcaaaggggaactgcaa C:60
E E V D L V C Y E Q L P D S D S E N E K P:20
. . . . . . G:721
gaaagagaggtatttgaatttgcttttaatgacttatttatagtgtatagagactgtaca C:60
D E P D G V N H P L L L A R R A E P Q R P:20
. . . . . . G:781
ccgtatgcagcgtgtctgaaatgcatttcattttatgcaagagtaagagaattaagatat C:60
H N I V C V C C K C N N Q L Q L V V E T P:20
. . . . . . G:841
tatagagattccgtgtatggagaaacattagaggctgaaaccaagacaccgttacatgag C:60
S Q D G L R A L Q Q L F M D T L S F V C P:20
. . . . . . G:865
ctgctgatacgctgttatagatgcctaaaacctctatgtccaacagataaattaaagcat C:60
P L C A A N Q P:20
. . . . . . G:865
ataactgaaaaaagaagattccataatatagctggaatatatacaggacagtgtcgtggg C:60
P:20
. . . . . . G:865
tgtcggacccgagcaagacacctaagacagcaacgacaagcgcgtagtgaaacactggtg C:60
P:20
G:865
taa C:3
P:7