HPV11 E7

Accession: H000090

NC: M14119.1

Uniprot: P04020

Protein: E7

Organism: Human papillomavirus type 11

Function

E7 protein is transforming protein. It binds to pRB/p107 and promotes its complete degradation.

Mutation

530-600

601-700

701-800

801-826

Legend:same sensemissenseinsertiondeletion

Mutation type	Position	DESC	Disease	Reference
missense	662	G → T (A → S)	Disease: Condyloma acuminate Region : Sichuan	Ref
same sense	685	A → T	Disease:	Ref

show more details

Domain&Motif

method	domain/motif name	position	length	description
CDD	PHA02776	530-820	291	E7 protein; Provisional
CDD	E7	536-814	279	E7 protein, Early protein;
MOTIF_SCAN		548-559	12
MOTIF_SCAN		623-634	12
MOTIF_SCAN		743-754	12
MOTIF_SCAN		707-724	18
MOTIF_SCAN		548-556	9
MOTIF_SCAN		530-559	30
MOTIF_SCAN		536-814	279
MOTIF_SCAN		674-715	42
MOTIF_SCAN		536-814	279
INTERPROSCAN		530-823	294
INTERPROSCAN		536-811	276
MOTIF_SEAR_IN_PROT		530-820	291
MOTIF_SEAR_IN_PROT		536-814	279
MOTIF_SEAR_IN_PROT		605-694	90
MOTIF_SEAR_IN_PROT		551-688	138
MOTIF_SEAR_IN_PROT		536-811	276
MOTIF_SEAR_IN_PROT		605-697	93
PROSITE_SCAN		548-556	9
PROSITE_SCAN		548-559	12
PROSITE_SCAN		623-634	12
PROSITE_SCAN		707-724	18
PROSITE_SCAN		743-754	12
SBASE		530-814	285
TMPRED_SERVER		767-820	54
TMPRED_SERVER		776-826	51
UNIPROTKB		701-811	111
UNIPROTKB		530-655	126
UNIPROTKB		596-610	15
UNIPROTKB		755-781	27

Sequence

         .         .         .         .         .         .　　　　　G:589
atgcatggaagacttgttaccctaaaggatatagtactagacctgcagcctcctgaccct　　　　　C:60
 M  H  G  R  L  V  T  L  K  D  I  V  L  D  L  Q  P  P  D  P 　　　　　P:20


         .         .         .         .         .         .　　　　　G:649
gtagggttacattgctatgagcaattagaagacagctcagaagatgaggtggacaaggtg　　　　　C:60
 V  G  L  H  C  Y  E  Q  L  E  D  S  S  E  D  E  V  D  K  V 　　　　　P:20


         .         .         .         .         .         .　　　　　G:709
gacaaacaagacgcacaacctttaacacaacattaccaaatactgacctgttgctgtgga　　　　　C:60
 D  K  Q  D  A  Q  P  L  T  Q  H  Y  Q  I  L  T  C  C  C  G 　　　　　P:20


         .         .         .         .         .         .　　　　　G:769
tgtgacagcaacgtccgactggttgtggagtgcacagacggagacatcagacaactacaa　　　　　C:60
 C  D  S  N  V  R  L  V  V  E  C  T  D  G  D  I  R  Q  L  Q 　　　　　P:20


         .         .         .         .         .          　　　　　G:826
gaccttttgctgggcacactaaatattgtgtgtcccatctgcgcaccaaaaccataa   　　　　　C:57
 D  L  L  L  G  T  L  N  I  V  C  P  I  C  A  P  K  P       　　　　　P:18

Legend:gene mutationamino acid mutation

DETAIL

DOMAIN & MUTATION