HPV11 E4

Accession: H000046

Uniprot: P04016

Protein: E4

Organism: Human papillomavirus type 11

Function

It is responsible for recognition and binding of origin of replication. It exists in two forms such as full length (transcriptional transactivator) and truncated (transcriptional repressor). The ratio of these found in the heterotrimeric complex, formed b

Domain&Motif

method	domain/motif name	position	length	description
CDD	PHA03417	3255-3578	324	E4 protein; Provisional
MOTIF_SCAN		3537-3548	12
MOTIF_SCAN		3549-3566	18
MOTIF_SCAN		3537-3545	9
MOTIF_SCAN		3366-3407	42
MOTIF_SCAN		3462-3563	102
MOTIF_SCAN		3309-3578	270
MOTIF_SCAN		3309-3578	270
INTERPROSCAN		3309-3578	270
MOTIF_SEAR_IN_PROT		3255-3578	324
MOTIF_SEAR_IN_PROT		3309-3578	270
MOTIF_SEAR_IN_PROT		3300-3578	279
MOTIF_SEAR_IN_PROT		3282-3371	90
MOTIF_SEAR_IN_PROT		3492-3578	87
MOTIF_SEAR_IN_PROT		3495-3569	75
MOTIF_SEAR_IN_PROT		3309-3578	270
PROSITE_SCAN		3537-3545	9
PROSITE_SCAN		3537-3548	12
PROSITE_SCAN		3549-3566	18
SBASE		3408-3578	171
TMPRED_SERVER		3270-3335	66
TMPRED_SERVER		3276-3332	57

Sequence

         .         .         .         .         .         .　　　　　G:3314
atggtagtaccaatcattgggaagtatgttatggcagcacagttatatgttctcctgcat　　　　　C:60
 M  V  V  P  I  I  G  K  Y  V  M  A  A  Q  L  Y  V  L  L  H 　　　　　P:20


         .         .         .         .         .         .　　　　　G:3374
ctgtatctagcactgtacgagaagtatccattgctgaacctactacatacacccccgcac　　　　　C:60
 L  Y  L  A  L  Y  E  K  Y  P  L  L  N  L  L  H  T  P  P  H 　　　　　P:20


         .         .         .         .         .         .　　　　　G:3434
agaccaccgcccctacagtgtccgcctgcaccacggaagacggcgtgtcggcgccgccta　　　　　C:60
 R  P  P  P  L  Q  C  P  P  A  P  R  K  T  A  C  R  R  R  L 　　　　　P:20


         .         .         .         .         .         .　　　　　G:3494
ggaagcgagcacgtggaccgtccactaacaacaccctgtgtgtggccaacatcagatccg　　　　　C:60
 G  S  E  H  V  D  R  P  L  T  T  P  C  V  W  P  T  S  D  P 　　　　　P:20


         .         .         .         .         .         .　　　　　G:3554
tggacagtacaatcaacaacatcgtcactgacaattacaacaagcaccaaagaaggaaca　　　　　C:60
 W  T  V  Q  S  T  T  S  S  L  T  I  T  T  S  T  K  E  G  T 　　　　　P:20


         .         .                                        　　　　　G:3581
actgtcacagtgcagctacgcctatag                                 　　　　　C:27
 T  V  T  V  Q  L  R  L                                     　　　　　P:8

DETAIL

DOMAIN & MUTATION