HPV121 E2
Accession: H003297
NC: YP_003668028.1
Protein: E2
Organism: Human papillomavirus type 12
Function
It is responsible for recognition and binding of origin of replication. It exists in two forms such as full length (transcriptional transactivator) and truncated (transcriptional repressor). The ratio of these found in the heterotrimeric complex, formed b
Sequence&Mutation
. . . . . . G:
ATGGAGAAGCTGAGAGAGCGCTTCGATGCTGTGCAAGAAGCTCTATTGACTCTATATGAA C:60
M E K L R E R F D A V Q E A L L T L Y E P:20
. . . . . . G:
AATGCTGCAAAAGACATTGATACACAAATACAGCACTGGGAATTATTAAGACAAGAGCAT C:60
N A A K D I D T Q I Q H W E L L R Q E H P:20
. . . . . . G:
GTTATTATGTATTATGCTAGACAAAATGGAATTAAAAGAATAGGCTTTCATCAGGTACCG C:60
V I M Y Y A R Q N G I K R I G F H Q V P P:20
. . . . . . G:
TCATTGGCTACCTCTGAACATAAAGCTAAAGAAGCCATCAGAATGACTATATTATTAAAA C:60
S L A T S E H K A K E A I R M T I L L K P:20
. . . . . . G:
TCTCTAAAAGACTCTCCTTTTGGTAGTGAGACATGGTCCTTAACAGAAACTAGTTTAGAA C:60
S L K D S P F G S E T W S L T E T S L E P:20
. . . . . . G:
ATAGTTAATGCAGCACCTAGTAATTGCTTTAAAAAAGAAGCCTATATTGTAGATGTATAT C:60
I V N A A P S N C F K K E A Y I V D V Y P:20
. . . . . . G:
TATGATAGGGATGCGGATAAAGTGTACCCTTATACTGGTTGGAAACATATATATTTCCAA C:60
Y D R D A D K V Y P Y T G W K H I Y F Q P:20
. . . . . . G:
GGAGAGGACAATATGTGGCATAAGACTCCTGGAAGAGTGGACTATTATGGACTGTATTAT C:60
G E D N M W H K T P G R V D Y Y G L Y Y P:20
. . . . . . G:
ATAGATGACTATGGGGATAAAGTATATTATGTAAATTTTGATGAAAAAGCACAAACCTTG C:60
I D D Y G D K V Y Y V N F D E K A Q T L P:20
. . . . . . G:
TCAGTTACTGGAGAATGGGAGGTGAAATATCAAAACAAAACTATTTCTCCCTCTGTTACC C:60
S V T G E W E V K Y Q N K T I S P S V T P:20
. . . . . . G:
TCTAGCTCCTCTCCCACTGCCTGGAAACCTGCTCAGGGGCACACCAGCCATTCCCCCTGG C:60
S S S S P T A W K P A Q G H T S H S P W P:20
. . . . . . G:
AACTCCGAAACTATCGAGGAGGTACGACGAAAGCAGGAGGGGCCCAAGAATACCTCTGTG C:60
N S E T I E E V R R K Q E G P K N T S V P:20
. . . . . . G:
CCCTCCAGTGAGGAAACACCTGGACTTCGACATAACAGAAGACGACGAGAAGGAGAATCA C:60
P S S E E T P G L R H N R R R R E G E S P:20
. . . . . . G:
GGAATTACCAGGAGCCCAAAGAGAAGAAGAACCGACATCCCAGACTCCACCGGACCTGCT C:60
G I T R S P K R R R T D I P D S T G P A P:20
. . . . . . G:
TACCCAACTCCTGCACAAGTGGGGAGTAGCCATCGATCAGCTAGCGGACATTATTCTTCA C:60
Y P T P A Q V G S S H R S A S G H Y S S P:20
. . . . . . G:
AGACTTGAAAGATTGCAAGCAGAAGCTCGGGATCCCCCAATAATAATTGTAAAAGGTTGT C:60
R L E R L Q A E A R D P P I I I V K G C P:20
. . . . . . G:
GCAAATACATTGAAATGCTGGAGATTTAGATTTAAAAAACAAAATAGAAAGTTATTTGAA C:60
A N T L K C W R F R F K K Q N R K L F E P:20
. . . . . . G:
CAGGCATCTACAGTGTTCAAATGGGTAGATTATGATAGTAGTAGCAGAATGTTATTATCC C:60
Q A S T V F K W V D Y D S S S R M L L S P:20
. . . . . . G:
TTTAAAGACACTGCACAAAGACAATTGTTTTTGGACACTGTCACACTACCAAAAGGAACC C:60
F K D T A Q R Q L F L D T V T L P K G T P:20
. . . G:
CAGGTTGCATTAGGATCATTAAACAGTTTGTAA C:33
Q V A L G S L N S L P:10