HPV4 E4
Accession: H003095
NC: NP_040893.1
Protein: E4
Organism: Human papillomavirus type 4
Function
It is responsible for recognition and binding of origin of replication. It exists in two forms such as full length (transcriptional transactivator) and truncated (transcriptional repressor). The ratio of these found in the heterotrimeric complex, formed b
Sequence&Mutation
. . . . . . G:3040
ATGAACAGTGGCACAAAGTTAAAGGTGAAGTGGATTATGATGGCTTATACTTTACAGACC C:60
M N S G T K L K V K W I M M A Y T L Q T P:20
. . . . . . G:3100
ATACGGGAGAAAGAGCTTATTTTACATTATTTAGCTCTGATGCTCAAAGATTTAGCAGAA C:60
I R E K E L I L H Y L A L M L K D L A E P:20
. . . . . . G:3160
CTGGACTGTGGACTGTGCATTTTAAAACCCAAGTTATTTCCTCCCCTATTGTTAGCTCTA C:60
L D C G L C I L K P K L F P P L L L A L P:20
. . . . . . G:3220
CATACTCCTCCTCCTTCGACACTGAGGAACAACAGTTACCCGGGCCCTCCACCAGCTACT C:60
H T P P P S T L R N N S Y P G P P P A T P:20
. . . . . . G:3280
CCGAAGTTACCGAGCAGGCGAGCCCTACTCGAAGGAGGAAACCGAGGAAATCCGACGCGA C:60
P K L P S R R A L L E G G N R G N P T R P:20
. . . . . . G:3340
CCTCCACCACGTCCCCTGAAACCGAGGGAGTACGACTACGACGAAGACGACGAGAAGGAA C:60
P P P R P L K P R E Y D Y D E D D E K E P:20
. . . . . . G:3400
AATCAGGGCCCGGGTCAGGAGAAACCCCCCGCAAAAGAAGAAGAGGAGGAGGAAGAGGAG C:60
N Q G P G Q E K P P A K E E E E E E E E P:20
. . . . . . G:3460
GAGGAGAGACCGAATTGGGATCTGCACCATCTCCTGCAGAAGTGGGGAGCAGACATCGAC C:60
E E R P N W D L H H L L Q K W G A D I D P:20
. . . . . . G:3520
AAGTTGAAAGACAAGGTCTGTCGCGACTTGGACTCTTACAAGCAGAAGCTAGGGATCCGC C:60
K L K D K V C R D L D S Y K Q K L G I R P:20
G:3526
CTATGA C:6
L P:1