HPV4 E2
Accession: H003094
NC: NP_040892.1
Protein: E2
Organism: Human papillomavirus type 4
Function
It is responsible for recognition and binding of origin of replication. It exists in two forms such as full length (transcriptional transactivator) and truncated (transcriptional repressor). The ratio of these found in the heterotrimeric complex, formed b
Sequence&Mutation
. . . . . . G:2613
ATGGAGTCCCTAGTCGCACGTTTCGATGCACTTCAAGAAGCAATTCTGACTCATATTGAG C:60
M E S L V A R F D A L Q E A I L T H I E P:20
. . . . . . G:2673
TCACAGGAGAGCACTTTGGAATCCCAAATCCAATATTGGGAAAATATCAGAAAAGAAAAT C:60
S Q E S T L E S Q I Q Y W E N I R K E N P:20
. . . . . . G:2733
GCTATAATGCATTATGCTCGAAAACAAGGCCTAACCAAATTAGGTCTACAACCACTTCCT C:60
A I M H Y A R K Q G L T K L G L Q P L P P:20
. . . . . . G:2793
ACACTAGCAGTAACTGAATACAATGCAAAGCAAGCTATTCAGATACATTTAACTTTGCAA C:60
T L A V T E Y N A K Q A I Q I H L T L Q P:20
. . . . . . G:2853
TCATTGTTAAAATCTCCCTTTGCATCTGAACGGTGGACATTGACAGATGTTAGTGCAGAA C:60
S L L K S P F A S E R W T L T D V S A E P:20
. . . . . . G:2913
CTGATAAATACCTCTCCACAAAACTGTTTAAAAAAGGGAGGTTATGATGTTGCTGTGTGG C:60
L I N T S P Q N C L K K G G Y D V A V W P:20
. . . . . . G:2973
TTTGATAATGATAGACAGAATGCAATGCTGTACACAAATTGGGACTTTTTATATTATCAA C:60
F D N D R Q N A M L Y T N W D F L Y Y Q P:20
. . . . . . G:3033
GATATGAATGAACAGTGGCACAAAGTTAAAGGTGAAGTGGATTATGATGGCTTATACTTT C:60
D M N E Q W H K V K G E V D Y D G L Y F P:20
. . . . . . G:3093
ACAGACCATACGGGAGAAAGAGCTTATTTTACATTATTTAGCTCTGATGCTCAAAGATTT C:60
T D H T G E R A Y F T L F S S D A Q R F P:20
. . . . . . G:3153
AGCAGAACTGGACTGTGGACTGTGCATTTTAAAACCCAAGTTATTTCCTCCCCTATTGTT C:60
S R T G L W T V H F K T Q V I S S P I V P:20
. . . . . . G:3213
AGCTCTACATACTCCTCCTCCTTCGACACTGAGGAACAACAGTTACCCGGGCCCTCCACC C:60
S S T Y S S S F D T E E Q Q L P G P S T P:20
. . . . . . G:3273
AGCTACTCCGAAGTTACCGAGCAGGCGAGCCCTACTCGAAGGAGGAAACCGAGGAAATCC C:60
S Y S E V T E Q A S P T R R R K P R K S P:20
. . . . . . G:3333
GACGCGACCTCCACCACGTCCCCTGAAACCGAGGGAGTACGACTACGACGAAGACGACGA C:60
D A T S T T S P E T E G V R L R R R R R P:20
. . . . . . G:3393
GAAGGAAAATCAGGGCCCGGGTCAGGAGAAACCCCCCGCAAAAGAAGAAGAGGAGGAGGA C:60
E G K S G P G S G E T P R K R R R G G G P:20
. . . . . . G:3453
AGAGGAGGAGGAGAGACCGAATTGGGATCTGCACCATCTCCTGCAGAAGTGGGGAGCAGA C:60
R G G G E T E L G S A P S P A E V G S R P:20
. . . . . . G:3513
CATCGACAAGTTGAAAGACAAGGTCTGTCGCGACTTGGACTCTTACAAGCAGAAGCTAGG C:60
H R Q V E R Q G L S R L G L L Q A E A R P:20
. . . . . . G:3573
GATCCGCCTATGATATTGTTAAAGGGCACAGCAAATTCTTTGAAATGTTGGAGATATAGA C:60
D P P M I L L K G T A N S L K C W R Y R P:20
. . . . . . G:3633
AAAGTTAACTCAAATTGCTGCAACTTCTTATTCATGAGTACTGTTTGGAACTGGGTTGGA C:60
K V N S N C C N F L F M S T V W N W V G P:20
. . . . . . G:3693
GATTGCTCACATAATCATAGTCGCATGCTTATTGCATTTGATAGCACTGACCAAAGAGAC C:60
D C S H N H S R M L I A F D S T D Q R D P:20
. . . . . . G:3753
GCTTTTGTAAAACACAACCTTTTTCCTAAACTGTGTACATATACCTACGGCTCATTGAAT C:60
A F V K H N L F P K L C T Y T Y G S L N P:20
G:3762
AGTTTATAA C:9
S L P:2