HPV50 E4
Accession: H003080
NC: NP_043427.1
Protein: E4
Organism: Human papillomavirus type 50
Function
It is responsible for recognition and binding of origin of replication. It exists in two forms such as full length (transcriptional transactivator) and truncated (transcriptional repressor). The ratio of these found in the heterotrimeric complex, formed b
Sequence&Mutation
. . . . . . G:3075
CTGGTGATTCAGTATACTTTAAACTCTTTCAACCTGATGCCACTGTATATGGCAAATCTG C:60
L V I Q Y T L N S F N L M P L Y M A N L P:20
. . . . . . G:3135
GACAATGGACTGTTATATTTAAAAACAAAACTATTCATTCCTCTGTCACTAGCTCCTCAA C:60
D N G L L Y L K T K L F I P L S L A P Q P:20
. . . . . . G:3195
GGAGTGCGTTTGGGCCTGCTGACGAACAGCCCGGGCCTTCCACATCGTACGACAAGAGCC C:60
G V R L G L L T N S P G L P H R T T R A P:20
. . . . . . G:3255
AACAGGAAAGATCTGGAAGCGGTCAACCAAAAGCCCTACAGGACACCGAACCACCCACCT C:60
N R K D L E A V N Q K P Y R T P N H P P P:20
. . . . . . G:3315
CGACATCAACAGTACGACTTCGACGAGGACGACGAGAAAGAGAACACCATTCCTACAGAC C:60
R H Q Q Y D F D E D D E K E N T I P T D P:20
. . . . . . G:3375
ACAGAAAGTCACAATCAGAATTGGGAGCCGACTCTGCGCCAACTCCTGAAGAAGTGGGAA C:60
T E S H N Q N W E P T L R Q L L K K W E P:20
. . . . . . G:3435
GAAGATCTCACACAGTTGCAGCGCATGGTCTGTCAAGACTTAGACGATTACAAGAGGAAG C:60
E D L T Q L Q R M V C Q D L D D Y K R K P:20
. . G:3456
CTCGGGATCCACCAGTCCTAA C:21
L G I H Q S P:6