HPV136 E4
Accession: H003078
NC: YP_006393292.1
Protein: E4
Organism: Human papillomavirus type 13
Function
It is responsible for recognition and binding of origin of replication. It exists in two forms such as full length (transcriptional transactivator) and truncated (transcriptional repressor). The ratio of these found in the heterotrimeric complex, formed b
Sequence&Mutation
. . . . . . G:3017
ATGGTACAGTGTCATACTTTCTACTATTTGAAAAGGATGCTAATAGATATGGACAAACAG C:60
M V Q C H T F Y Y L K R M L I D M D K Q P:20
. . . . . . G:3077
GAATGTGGACTGTTAATGTTAAAAATAAGCAAATTCTTCCTCCCTCTGTTGGTAGCTCTG C:60
E C G L L M L K I S K F F L P L L V A L P:20
. . . . . . G:3137
CTAGGAGGTCTGTATCTGAATCCCAGAGCAACGGGACCCAATCCCCCTTCAACACCCAGA C:60
L G G L Y L N P R A T G P N P P S T P R P:20
. . . . . . G:3197
CTGAAGAGACGGTCGGAGGAAGACAGATTCCTCAAGAAGCGGCAGGACCTAGTTCAACCA C:60
L K R R S E E D R F L K K R Q D L V Q P P:20
. . . . . . G:3257
CGACATCACCTAAAAGAGGACAACGACGACGACGAGGAGGAGAAGGAGAACAGACCACCA C:60
R H H L K E D N D D D E E E K E N R P P P:20
. . . . . . G:3317
ATAAGAGACGACGACGAGCTGAAGGACGTGGAGGAACTGCTGACATTACTGCTGAGGAAG C:60
I R D D D E L K D V E E L L T L L L R K P:20
. . . . . . G:3377
TTGGGCAAAGCCATCGATCAGTACCAGCAGCAGGTCTTACAAGAGTTGAGCGACTTAAAG C:60
L G K A I D Q Y Q Q Q V L Q E L S D L K P:20
. . G:3401
CAGAGGCTCGGGATCCGCCATTAG C:24
Q R L G I R H P:7