HPV140 E4
Accession: H003073
NC: YP_006393306.1
Protein: E4
Organism: Human papillomavirus type 14
Function
It is responsible for recognition and binding of origin of replication. It exists in two forms such as full length (transcriptional transactivator) and truncated (transcriptional repressor). The ratio of these found in the heterotrimeric complex, formed b
Sequence&Mutation
. . . . . . G:3100
ATGTTAACAATGAACAAATCTTCCCTTCTGTTGCCAGTTCTTCTAGGAGGTCTTCACCTG C:60
M L T M N K S S L L L P V L L G G L H L P:20
. . . . . . G:3160
TCTCCCCGAAAACCCTCGGGGACACAGACAGGAGATCAAGCAGCCCCACCACCTACACCA C:60
S P R K P S G T Q T G D Q A A P P P T P P:20
. . . . . . G:3220
AGACCCCGCAGAAAGACGGAGGAAGATCGATTCAGCAGGAGGAGGCAAGCACTAGCTCTG C:60
R P R R K T E E D R F S R R R Q A L A L P:20
. . . . . . G:3280
CCACCAGGACATCAGGAAGGAGACGACGACGACGAGGAGAAGGAGAACCGACCACCAGTA C:60
P P G H Q E G D D D D E E K E N R P P V P:20
. . . . . . G:3340
AGAGAAGAAGAAGAGGAGAACGTCATATCCTCTCTGCTGAAGAGGTTGGAAGTAGCCATC C:60
R E E E E E N V I S S L L K R L E V A I P:20
. . . . . . G:3400
GATCTGTTCCACGATCAGGTCTCTCAAGAATTGAAAGACTTGAAGAGGAAGCTAGGGATC C:60
D L F H D Q V S Q E L K D L K R K L G I P:20
. G:3418
CACCAATCCTCGTGGTGA C:18
H Q S S W P:5