HPV137 E4
Accession: H003072
NC: YP_006393299.1
Protein: E4
Organism: Human papillomavirus type 13
Function
It is responsible for recognition and binding of origin of replication. It exists in two forms such as full length (transcriptional transactivator) and truncated (transcriptional repressor). The ratio of these found in the heterotrimeric complex, formed b
Sequence&Mutation
. . . . . . G:3121
ATGAACAACTTTCCTCCTCTATTGCTAGCTCTACTCGGCGGCCTATACCCCTCCTCTCCC C:60
M N N F P P L L L A L L G G L Y P S S P P:20
. . . . . . G:3181
ACGAAACCAACAGGAACGGGAACGGAGCTTCCCGCGCGACCACCAGGAACGCCAGCCCTA C:60
T K P T G T G T E L P A R P P G T P A L P:20
. . . . . . G:3241
CATCGACGGCGCTCCCCATCTCTTCTTACGGAGGAAGAGAGGAATCGGAATCGGAGGAGG C:60
H R R R S P S L L T E E E R N R N R R R P:20
. . . . . . G:3301
GCCCTAGCTCTACCAGCAGGTCGCCAACGGGACGACGACGACGACGAAGAGGAGGGGAAC C:60
A L A L P A G R Q R D D D D D E E E G N P:20
. . . . . . G:3361
AAGGAGAATCAGCCGCCAGACCACAGAAGAGAAAGCGAGGAGGTGACGCTGTTCCAACTG C:60
K E N Q P P D H R R E S E E V T L F Q L P:20
. . . . . . G:3421
CTGCAGAAGTTGGAAGCAATCATAGAACAGTTCCTTCAACGGGTCTCTCGCGACTTACAA C:60
L Q K L E A I I E Q F L Q R V S R D L Q P:20
. . . G:3460
GACTTCAGGCAGAAGCTAGGGACCCTCAACTCATCCTAA C:39
D F R Q K L G T L N S S P:12