HPV146 E4

Accession: H003068
NC: AEM24674.1
Protein: E4
Organism: Human papillomavirus type 14

Function

It is responsible for recognition and binding of origin of replication. It exists in two forms such as full length (transcriptional transactivator) and truncated (transcriptional repressor). The ratio of these found in the heterotrimeric complex, formed b

Sequence&Mutation

         .         .         .         .         .         .
MLKGIHKQDC LLNTKIQLS LLLLAPPGT ATPRKASSP APPSESPYR RGPQVGDDL
. . . . . .
KGILKKGFQL PPHRRPQAE DDDEEENEE KENTPPPPE PLDPNDKGP HQLLQKWGD
. .
DIDQFRRTIW DLEDFKRRL IHLLSV