HPV5 E5
Accession: H002916
NC: NP_041370.1
Protein: E5
Organism: Human papillomavirus type 5
Function
It obstructs the growth suppression mechanisms: e.g. EGF receptor; activates mitogenic signalling pathways via transcription factors: c-Jun and c-Fos (important in ubiquitin pathway degradation of p53 complex by E6). Also inactivates p21 protein (p53 indu
Sequence&Mutation
. . . . . . G:3465
CTCCACGTCCAGACAGCTCACCACATCAAAACAGCCACAACAAACCGAAACCAGAGGAAG C:60
L H V Q T A H H I K T A T T N R N Q R K P:20
. . . . . . G:3525
AAGGTACGGACGGAGGCCCTCCAGCAAGTCAAGGAGATCGCAAACGCAGCAAAGGCGATC C:60
K V R T E A L Q Q V K E I A N A A K A I P:20
. . . . . . G:3585
AAGGTCCCGACACCGGTCCCGGTCTCGGTCCCGGTCGCGGTCCAAGTCCCAAACCCACAC C:60
K V P T P V P V S V P V A V Q V P N P H P:20
. . . . . . G:3645
CACTCGGTCCACCACCAGGTCCCGGTCCACGTCGCTCACCAAGACTCGGGCCCTTACAAG C:60
H S V H H Q V P V H V A H Q D S G P Y K P:20
. . . . . . G:3705
CAGATCGCGATCCAGAGGAAGGTCCCCAACCACCTGCAGAAGGGGAGGTGGAAGGTCACC C:60
Q I A I Q R K V P N H L Q K G R W K V T P:20
. . . . . . G:3765
CAGGCGGCGATCAAGGTCACCCTCCACCTCCTCCTCCTGCACCACACAACGGTCACAGCG C:60
Q A A I K V T L H L L L L H H T T V T A P:20
. . . . . . G:3825
GGCACGAGCCGAAAGTTCAACAACCAGAGGGGCCCGAGGGTCGAGAGGGTCACGAGGAGG C:60
G T S R K F N N Q R G P R V E R V T R R P:20
. . . . . . G:3885
GAGCCGTGGGGGGAGAGGGCGGCGACGAGGAAGGTCATCCTCCTCCTCCTCCCCCGCCCA C:60
E P W G E R A A T R K V I L L L L P R P P:20
. . G:3912
CAAACGGTCACGAGGGGGGTCTGCTAA C:27
Q T V T R G V C P:8