HPV16 E2

Accession: H002737

Uniprot: S4W2B8

Protein: E2

Organism: Human papillomavirus type 16

Function

It is responsible for recognition and binding of origin of replication. It exists in two forms such as full length (transcriptional transactivator) and truncated (transcriptional repressor). The ratio of these found in the heterotrimeric complex, formed b

Sequence&Mutation

         .         .         .         .         .         .
METLCQRLNV QDKILTHYE DSTDLRDHI YWKHMRLEC IYYKAREMG KHINHQVVP
         .         .         .         .         .         .
TLAVSKNKAL AIELQLTLE IYNSQYSNE WTLQDVSLE YLTAPTGCI KHGYTVEVQ
         .         .         .         .         .         .
FDGDICNTMH TNWTHIYIC EASVTVVEG VDYYGLYYV EGIQTYFVQ KDDAEKYSK
         .         .         .         .         .         .
NKVWEVHAGG VILCPTSVF SNEVSSPEI RQHLANHTA THTKAVALG EETQTTIQR
         .         .         .         .         .         .
PRSEPDTGNP HTTKLLHRD VDSAPILTA NSSHKGRIN NSNTTPIVH KGDANTLKC
         .         .         .         .         .         .
LRYRFKKHCT YTAVSSTWH TGHNVKHKS IVTLTYDSE QRDQFLSQV IPKTITVST
                                                            
GFMSI     

Epitope&Mutation

>H002737_E2
METLCQRLNVCQDKILTHYENDSTDLRDHIDYWKHMRLECAIYYKAREMGFKHINHQVVPTLAVSKNKALQAIELQLTLETIYNSQYSNEKWTLQDVSLEVYLTAPTGCIKKHGYTVEVQFDGDICNTMHYTNWTHIYICEEASVTVVEGQVDYYGLYYVHEGIQTYFVQFKDDAEKYSKNKVWEVHAGGQVILCPTSVFSSNEVSSPEIIRQHLANHTAATHTKAVALGTEETQTTIQRPRSEPDTGNPCHTTKLLHRDSVDSAPILTAFNSSHKGRINCNSNTTPIVHLKGDANTLKCLRYRFKKHCTLYTAVSSTWHWTGHNVKHKSAIVTLTYDSEWQRDQFLSQVKIPKTITVSTGFMSI
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