HPV59 E5

Accession: H002641

Uniprot: T2A663

Protein: E5

Organism: Human papillomavirus type 59

Function

It obstructs the growth suppression mechanisms: e.g. EGF receptor; activates mitogenic signalling pathways via transcription factors: c-Jun and c-Fos (important in ubiquitin pathway degradation of p53 complex by E6). Also inactivates p21 protein (p53 indu

Sequence&Mutation

         .         .         .         .         .         .
MITLVFVCCV VCLCVCCNV LLQSVYMCA AWLLVFVYI VITSSYECF LYILFFIIP
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LLLLYAHAIL IQ