HPV16 E7

Accession: H002615

Uniprot: S4S8Q9

Protein: E7

Organism: Human papillomavirus type 16

Function

E7 protein is transforming protein. It binds to pRB/p107 and promotes its complete degradation.

Sequence&Mutation

         .         .         .         .         .         .
MHGDTPTLHE KLDLQPETT LYCYEQLND PEEEDGIDG AGQAEPDRA YNIVTFCCK
         .         .         .                              
CDSTLRLRVL IHVDIRTLE LLMDTLGIV P  

Epitope&Mutation

>H002615_E7
MHGDTPTLHEYKLDLQPETTDLYCYEQLNDSPEEEDGIDGPAGQAEPDRAHYNIVTFCCKCDSTLRLRVLSIHVDIRTLEDLLMDTLGIVCP
·HGDTPTLHEY(A1)·············································································
·················ETTDLYCYE(A1)······························································
···········································QAEPDRAHY(B18)···································
···············································DRAHYNIVTFCCKCD(DR15)························
················································RAHYNIVTF(A*0201)···························
················································RAHYNIVTF(A24)······························
·················································AHYNIVTFCCKCD(DR15)························
·························································CCKCDSTL(B8)·······················
········································································HVDIRTLED(A2)·······