HPV16 E2

Accession: H002588

Uniprot: S4W4K3

Protein: E2

Organism: Human papillomavirus type 16

Function

It is responsible for recognition and binding of origin of replication. It exists in two forms such as full length (transcriptional transactivator) and truncated (transcriptional repressor). The ratio of these found in the heterotrimeric complex, formed b

Sequence&Mutation

         .         .         .         .         .         .
METLCQRLNV QDKILTHYE DSTDLRDHI YWKHMRLEC IYYKAREMG KHINHQVVP
         .         .         .         .         .         .
TLAVSKNKAL AIELQLTLE IYNSQYSNE WTLQDVSLE YLTAPTGCI KHGYTVEVQ
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FDGDICNTMH TNWTHIYIC EASVTVVEG VDYYGLYYV EGIRTYFVQ KDDAEKYSK
         .         .         .         .         .         .
NKVWEVHAGG VILCPTSVF SNEVSSPEI RQHLANHSA THTKAVALG EETQTTIQR
         .         .         .         .         .         .
PRSEPDTGNP HTTKLLHRD VDSAPILTA NSSHKGRIN NSNSTPIVH KGDANTLKC
         .         .         .         .         .         .
LRYRFKKHCK YTAVSSTWH TGHNVKHKS IVTLTYDSE QRDQFLSQV IPKTITVST
                                                            
GFMSI     

Epitope&Mutation

>H002588_E2
METLCQRLNVCQDKILTHYENDSTDLRDHIDYWKHMRLECAIYYKAREMGFKHINHQVVPTLAVSKNKALQAIELQLTLETIYNSQYSNEKWTLQDVSLEVYLTAPTGCIKKHGYTVEVQFDGDICNTMHYTNWTHIYICEEASVTVVEGQVDYYGLYYVHEGIRTYFVQFKDDAEKYSKNKVWEVHAGGQVILCPTSVFSSNEVSSPEIIRQHLANHSAATHTKAVALGTEETQTTIQRPRSEPDTGNPCHTTKLLHRDSVDSAPILTAFNSSHKGRINCNSNSTPIVHLKGDANTLKCLRYRFKKHCKLYTAVSSTWHWTGHNVKHKSAIVTLTYDSEWQRDQFLSQVKIPKTITVSTGFMSI
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