HPV16 E1

Accession: H002550

Uniprot: R9QBM2

Protein: E1

Organism: Human papillomavirus type 16

Function

ATP-dependent DNA helicase required for initiation of viral DNA replication. It forms a complex with the viral E2 protein.

Sequence&Mutation

         .         .         .         .         .         .
LYGVSFSELE LFKSNKSTC DWCIASFGL PSIVDSIKT LQQYCLYLH QSLACSWGM
         .         .         .         .         .         .
VVLLLVRFKC KNRETIEKL SKLLCVSPM MMIEPPKLR TAAALYWYK GISNISELY
         .         .         .         .                    
GDTPEWIQRQ ILHHSFNDC FELSQMVQW YDNDIVDDS IA 

Epitope&Mutation

>H002550_E1
LYGVSFSELERLFKSNKSTCCDWCIASFGLTPSIVDSIKTLLQQYCLYLHIQSLACSWGMVVLLLVRFKCGKNRETIEKLLSKLLCVSPMCMMIEPPKLRSTAAALYWYKTGISNISELYGDTPEWIQRQTILHHSFNDCTFELSQMVQWAYDNDIVDDSEIA
·······································TLLQQYCLYL(A*0201)··········································································································
········································LLQQYCLYL(A2)··············································································································