HPV16 E1

Accession: H002484

Uniprot: R9QBJ5

Protein: E1

Organism: Human papillomavirus type 16

Function

ATP-dependent DNA helicase required for initiation of viral DNA replication. It forms a complex with the viral E2 protein.

Sequence&Mutation

         .         .         .         .         .         .
LYGVSFSELL PFKSNKSTC DWFIAAFGL PSIADSIKT LQQYCLYLH QSLACSWGM
         .         .         .         .         .         .
VVLLLVSYKC KNRETIEKL SKLLCVSPM MMLEPPKLR TAAALYWYK RISTISEVY
         .         .         .         .                    
GATPEWIQRQ ILQHSFNDC FELSQMVQW YDNDIVDDS IA 

Epitope&Mutation

>H002484_E1
LYGVSFSELLRPFKSNKSTCCDWFIAAFGLTPSIADSIKTLLQQYCLYLHIQSLACSWGMVVLLLVSYKCGKNRETIEKLLSKLLCVSPMYMMLEPPKLRRTAAALYWYKTRISTISEVYGATPEWIQRQSILQHSFNDCTFELSQMVQWAYDNDIVDDSEIA
·······································TLLQQYCLYL(A*0201)··········································································································
········································LLQQYCLYL(A2)··············································································································