HPV16 E2

Accession: H002448

Uniprot: S4W8B5

Protein: E2

Organism: Human papillomavirus type 16

Function

It is responsible for recognition and binding of origin of replication. It exists in two forms such as full length (transcriptional transactivator) and truncated (transcriptional repressor). The ratio of these found in the heterotrimeric complex, formed b

Sequence&Mutation

         .         .         .         .         .         .
METLCQRLNV QDKILTHYE DSTDLRDHI YWKHMRLEC IYYKAREMG KHINHQVVP
         .         .         .         .         .         .
TLAVSKNKAL AIELQLTLE IYNSQYSNE WTLQDVSLE YLTTPTGCI KHGYTVEVQ
         .         .         .         .         .         .
FDGDICNTMH TNWKHIYIC EASVTVVEG VDYYGLYYV EGIQTYFVQ KDDAEKYSK
         .         .         .         .         .         .
NKVWEVHAGG VILCPTSVF QHLANHSAA HTKAVALGT ETQTTIQRP SEPDTGNPC
         .         .         .         .         .         .
HTTKLLHRDS DSAPILTAF SSHKGRINC SNTTPIVHL GDANTLKCL YRFKKHCKL
         .         .         .         .         .          
YTAVSSTWHW GHNVKHKSA VTLTYDSEW RDQFLSQVK PKTITVSTG MSI

Epitope&Mutation

>H002448_E2
METLCQRLNVCQDKILTHYENDSTDLRDHIDYWKHMRLECAIYYKAREMGFKHINHQVVPTLAVSKNKALQAIELQLTLETIYNSQYSNEKWTLQDVSLEVYLTTPTGCIKKHGYTVEVQFDGDICNTMHYTNWKHIYICEEASVTVVEGQVDYYGLYYVHEGIQTYFVQFKDDAEKYSKNKVWEVHAGGQVILCPTSVFRQHLANHSAATHTKAVALGTEETQTTIQRPRSEPDTGNPCHTTKLLHRDSVDSAPILTAFNSSHKGRINCNSNTTPIVHLKGDANTLKCLRYRFKKHCKLYTAVSSTWHWTGHNVKHKSAIVTLTYDSEWQRDQFLSQVKIPKTITVSTGFMSI
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