HPV16 E7

Accession: H002425

Uniprot: S4S7V5

Protein: E7

Organism: Human papillomavirus type 16

Function

E7 protein is transforming protein. It binds to pRB/p107 and promotes its complete degradation.

Sequence&Mutation

         .         .         .         .         .         .
MHGDTPTLHE KLDLQPETT LYCYEQLNH SEGEDEIDG AGQAEPDRA YNIVTFCCK
         .         .         .                              
CDSTPRLCVQ THVDIRTLE LLMDTLGIV P  

Epitope&Mutation

>H002425_E7
MHGDTPTLHEYKLDLQPETTDLYCYEQLNHSSEGEDEIDGPAGQAEPDRAHYNIVTFCCKCDSTPRLCVQSTHVDIRTLEDLLMDTLGIVCP
·HGDTPTLHEY(A1)·············································································
·················ETTDLYCYE(A1)······························································
··································EDEIDGPAGQAEPDRA(DQ2)·····································
···········································QAEPDRAHY(B18)···································
···············································DRAHYNIVTFCCKCD(DR15)························
················································RAHYNIVTF(A*0201)···························
················································RAHYNIVTF(A24)······························
·················································AHYNIVTFCCKCD(DR15)························
··································································LCVQSTHVDI(A*2402)········
········································································HVDIRTLED(A2)·······