HPV16 E1

Accession: H002422

Uniprot: R9QBE7

Protein: E1

Organism: Human papillomavirus type 16

Function

ATP-dependent DNA helicase required for initiation of viral DNA replication. It forms a complex with the viral E2 protein.

Sequence&Mutation

         .         .         .         .         .         .
LYGVSFSELV PFKSNKSSC DWCIAAFGL PSIADSIKT LQQYCLYLH QSLACSWRM
         .         .         .         .         .         .
VVLLLVRYKC KNRETIEKL SKLLCVSPM MMIEPPKLR TAAALYWYK GISNISEVY
         .         .         .         .                    
GDTPEWIQRQ ILQHSFNDC FELSQMVQW YVNDIVDDS IA 

Epitope&Mutation

>H002422_E1
LYGVSFSELVRPFKSNKSSCCDWCIAAFGLTPSIADSIKTLLQQYCLYLHIQSLACSWRMVVLLLVRYKCGKNRETIEKLLSKLLCVSPMCMMIEPPKLRITAAALYWYKTGISNISEVYGDTPEWIQRQSILQHSFNDCTFELSQMVQWAYVNDIVDDSEIA
·······································TLLQQYCLYL(A*0201)··········································································································
········································LLQQYCLYL(A2)··············································································································