HPV16 E1

Accession: H002323

Uniprot: R9QBD0

Protein: E1

Organism: Human papillomavirus type 16

Function

ATP-dependent DNA helicase required for initiation of viral DNA replication. It forms a complex with the viral E2 protein.

Sequence&Mutation

         .         .         .         .         .         .
LYGVSFSELV PFKSNKSTC DWCIAAFGL PSIADRIKT LQQYCLYLH QSLACSWGM
         .         .         .         .         .         .
VVLLLVRYKC KNRETIEKL SKLLCVSPM MMIEPPKLR TAAALYWYK GISNINEVY
         .         .         .         .                    
GDTPEWIQRQ VLQHSFNDC FELSQMVQW YDNDIVDDS IA 

Epitope&Mutation

>H002323_E1
LYGVSFSELVRPFKSNKSTCCDWCIAAFGLTPSIADRIKTLLQQYCLYLHIQSLACSWGMVVLLLVRYKCGKNRETIEKLLSKLLCVSPMCMMIEPPKLRSTAAALYWYKTGISNINEVYGDTPEWIQRQTVLQHSFNDCTFELSQMVQWAYDNDIVDDSEIA
·······································TLLQQYCLYL(A*0201)··········································································································
········································LLQQYCLYL(A2)··············································································································