HPV16 E1

Accession: H002281

Uniprot: R9QBE8

Protein: E1

Organism: Human papillomavirus type 16

Function

ATP-dependent DNA helicase required for initiation of viral DNA replication. It forms a complex with the viral E2 protein.

Sequence&Mutation

         .         .         .         .         .         .
LYGVSFSELV PFKSNKSTC DWCIAAIGL PSIADSIKT LQQYCLYLH QSLACSWGM
         .         .         .         .         .         .
VVLLLVRYKC TNRETIEKL SKLLCVSPM MMIEPPKLR TAAALYWYK GISNISEMY
         .         .         .         .                    
GDTPEWIQRQ ILQHSFNDC FELSQMVQW YDNDIVDDS IA 

Epitope&Mutation

>H002281_E1
LYGVSFSELVRPFKSNKSTCCDWCIAAIGLTPSIADSIKTLLQQYCLYLHIQSLACSWGMVVLLLVRYKCGTNRETIEKLLSKLLCVSPMCMMIEPPKLRITAAALYWYKTGISNISEMYGDTPEWIQRQTILQHSFNDCTFELSQMVQWAYDNDIVDDSEIA
·······································TLLQQYCLYL(A*0201)··········································································································
········································LLQQYCLYL(A2)··············································································································