HPV16 E1

Accession: H002226

Uniprot: R9QBK0

Protein: E1

Organism: Human papillomavirus type 16

Function

ATP-dependent DNA helicase required for initiation of viral DNA replication. It forms a complex with the viral E2 protein.

Sequence&Mutation

         .         .         .         .         .         .
LYGVSFSELV PFKSNKTTC DWCIATFGL PSIADSIKT LQQYCLYLH KSLASSWGM
         .         .         .         .         .         .
VVLLLVRYIC KNRETIEKL SKLLCVSPL MMIEPPKLR TAAALYWNK GILNISEVY
         .         .         .         .                    
GDTPKWIQRQ VLQHSFNDC FELSQMVQW YDNDIVDDS IA 

Epitope&Mutation

>H002226_E1
LYGVSFSELVRPFKSNKTTCCDWCIATFGLTPSIADSIKTLLQQYCLYLHIKSLASSWGMVVLLLVRYICGKNRETIEKLLSKLLCVSPLCMMIEPPKLRSTAAALYWNKTGILNISEVYGDTPKWIQRQTVLQHSFNDCTFELSQMVQWAYDNDIVDDSEIA
·······································TLLQQYCLYL(A*0201)··········································································································
········································LLQQYCLYL(A2)··············································································································