HPV16 E2

Accession: H002111

Uniprot: I1SV07

Protein: E2

Organism: Human papillomavirus type 16

Function

It is responsible for recognition and binding of origin of replication. It exists in two forms such as full length (transcriptional transactivator) and truncated (transcriptional repressor). The ratio of these found in the heterotrimeric complex, formed b

Sequence&Mutation

         .         .         .         .         .         .
METLCQRLNV QEKILTHYE DSTDLRDHI YWKQMRLEC IYYKAREMG KHINHQVVP
         .         .         .         .         .         .
TLAVSKNKAL AIELQLTLE IYNSQYSNE WTLQDVSLE YLTALTGCI KHGYTVDVQ
         .         .         .         .         .         .
FDGDICNTMH TNWRFIYIC ETSVTVVEG VDYYGIYYV EGIQTYFVQ RDDAEKYSK
         .         .                                        
NKVWEVHAGG VILCPTSVF SNE   

Epitope&Mutation

>H002111_E2
METLCQRLNVCQEKILTHYENDSTDLRDHIDYWKQMRLECAIYYKAREMGFKHINHQVVPTLAVSKNKALQAIELQLTLETIYNSQYSNEKWTLQDVSLEVYLTALTGCIKKHGYTVDVQFDGDICNTMHYTNWRFIYICEETSVTVVEGQVDYYGIYYVHEGIQTYFVQFRDDAEKYSKNKVWEVHAGGQVILCPTSVFSSNE
····································································ALQAIELQL(A*0201)·······················································································································
····························································································TLQDVSLEV(A*0201)·······························································································