HPV16 E1

Accession: H002087

Uniprot: J3T1T7

Protein: E1

Organism: Human papillomavirus type 16

Function

ATP-dependent DNA helicase required for initiation of viral DNA replication. It forms a complex with the viral E2 protein.

Sequence&Mutation

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MADPAGTNGE GTGCNGWFY EAVVEKKTG AISDDENEN SDTGEDLVD IVNDNDYLT
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QAETETAHAL TAQEAKEHR AVQVLKRKY GSPLSDISE VDNNISPRL AICIEKQSR
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AAKRRLFESE SGYGNTEVE QQMLQVEGR ETETPCSQY GGSGGSSSQ SSGSGGEGV
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SERHTICETP TNILNVLKT NAKAAMLAK KELYGVSFT LVRPFKSNK TCCDWCIAA
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FGLTPSIADS KTLLQQYCL LHIQSLACS GMVVLLLVR KCGKNRETI KLMSKLLCV
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PPMCMMIEPP LRSTAAALY YKTGMSNIS VCGDTPEWI RQTVLQHSF NCTFELSQM
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VQWAYDNDIV DSEIAYKYA LADTNSNAS FLKSNSQAK VKDCATMCR YKRAEKKQM
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SMSQWIKYRC RVDDGGDWK IVMFLRYQG DFMSFLSAL KFLQGIPKK CILLYGAAN
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TGKSLFGMSL KFLQGSVIC VNSKSHFWL PLADAKIGM DDATVPCWN IDDNLRNAL
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DGNLVSMDVK RPLVQLKCP LLITSNINA TDSRWPYLH RLVVFTFPN FPFDKNGNP
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VYELNDKNWK FFSRTWSRL LHEDEDKEN GDSLPTFKC SGQNTNTL 

Epitope&Mutation

>H002087_E1
MADPAGTNGEEGTGCNGWFYVEAVVEKKTGDAISDDENENDSDTGEDLVDFIVNDNDYLTQAETETAHALFTAQEAKEHRDAVQVLKRKYLGSPLSDISECVDNNISPRLKAICIEKQSRAAKRRLFESEDSGYGNTEVETQQMLQVEGRHETETPCSQYSGGSGGSSSQYSSGSGGEGVSERHTICETPLTNILNVLKTSNAKAAMLAKFKELYGVSFTELVRPFKSNKSTCCDWCIAAFGLTPSIADSIKTLLQQYCLYLHIQSLACSWGMVVLLLVRYKCGKNRETIEKLMSKLLCVPPMCMMIEPPKLRSTAAALYWYKTGMSNISEVCGDTPEWIQRQTVLQHSFNNCTFELSQMVQWAYDNDIVDDSEIAYKYAQLADTNSNASAFLKSNSQAKIVKDCATMCRHYKRAEKKQMSMSQWIKYRCDRVDDGGDWKQIVMFLRYQGVDFMSFLSALKKFLQGIPKKNCILLYGAANTGKSLFGMSLMKFLQGSVICFVNSKSHFWLQPLADAKIGMLDDATVPCWNYIDDNLRNALDGNLVSMDVKHRPLVQLKCPPLLITSNINAGTDSRWPYLHNRLVVFTFPNEFPFDKNGNPVYELNDKNWKSFFSRTWSRLSLHEDEDKENDGDSLPTFKCVSGQNTNTL
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