HPV16 E2

Accession: H001995

Uniprot: G0XRL1

Protein: E2

Organism: Human papillomavirus type 16

Function

It is responsible for recognition and binding of origin of replication. It exists in two forms such as full length (transcriptional transactivator) and truncated (transcriptional repressor). The ratio of these found in the heterotrimeric complex, formed b

Sequence&Mutation

         .         .         .         .         .         .
AGGQVILCPT AFSSNVVSS EIIRQHLAN SAATHTKAV LGIEETQTT QRPRSEPDT
         .         .         .         .         .         .
GNPCHTTKLL RDSVDSAPI TPFNSSHNG INCNSNTTP VHFKGDANT KCLRYRFKK
         .         .         .         .         .          
HCTLYNAVSS WHWTGHNVK KSAIVTLTY SEWQRDQFL QVKIPKTIT STGFMSI

Epitope&Mutation

>H001995_E2
AGGQVILCPTSAFSSNVVSSPEIIRQHLANHSAATHTKAVALGIEETQTTIQRPRSEPDTGNPCHTTKLLHRDSVDSAPILTPFNSSHNGRINCNSNTTPIVHFKGDANTLKCLRYRFKKHCTLYNAVSSTWHWTGHNVKHKSAIVTLTYDSEWQRDQFLSQVKIPKTITVSTGFMSI
································································································································SSTWHWTGHNVKHKS(DRB1*1502)························
································································································································SSTWHWTGHNVKHKSAIVTLTYDSEWQRDQ(DR)················
································································································································SSTWHWTGHNVKHKSAIVTLTYDSEWQRDQ(DR1)···············
································································································································SSTWHWTGHNVKHKSAIVTLTYDSEWQRDQ(DR2)···············
································································································································SSTWHWTGHNVKHKSAIVTLTYDSEWQRDQ(DR3)···············
··············································································································································AIVTLTYDSEWQRDQFLSQVKIPKTITVSTGFMSI(DR)
··············································································································································AIVTLTYDSEWQRDQFLSQVKIPKTITVSTGFMSI(DR1)
··············································································································································AIVTLTYDSEWQRDQFLSQVKIPKTITVSTGFMSI(DR2)
··············································································································································AIVTLTYDSEWQRDQFLSQVKIPKTITVSTGFMSI(DR3)
··············································································································································AIVTLTYDSEWQRDQFLSQVKIPKTITVSTGFMSI(DR4)
······························································································································································FLSQVKIPKT(DR15)····
··································································································································································KIPKTITVSTGFMSI(DR1)