HPV16 E2

Accession: H001987

Uniprot: J3XLW2

Protein: E2

Organism: Human papillomavirus type 16

Function

It is responsible for recognition and binding of origin of replication. It exists in two forms such as full length (transcriptional transactivator) and truncated (transcriptional repressor). The ratio of these found in the heterotrimeric complex, formed b

Sequence&Mutation

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METLCQRLNV QDKILTHYE DSTDLRDHI YWKQMRLEC IYYKAREMG KHINHQVVP
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TLAVSKNKAL AIELQLTLE IYNSQYSNE WTLQDVSLE YLTAPTGCI KHGYTVEVQ
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FDGDICNTMH TNWKYIYIC ETSVTVVEG VDYYGLYYV EGIQTYFVQ KDDAEKYSK
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NKVWEVHAGG VILCPTSVF SDEVSSAEI RQHLANHSA THTKTVALG KETQTTIQR
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PRSEPDTGNP HTNKLLHRD VDSAPILTA NSSHKGRIN NSNTTPIVH KGDANTLKC
         .         .         .         .         .         .
LRYRFKKHCK YTAVSSTWH TGHNVKHKS IVTLTYDSE QREQFLSQV IPKTITVST
                                                            
GFMSI     

Epitope&Mutation

>H001987_E2
METLCQRLNVCQDKILTHYENDSTDLRDHIDYWKQMRLECAIYYKAREMGFKHINHQVVPTLAVSKNKALQAIELQLTLETIYNSQYSNEKWTLQDVSLEVYLTAPTGCIKKHGYTVEVQFDGDICNTMHYTNWKYIYICEETSVTVVEGQVDYYGLYYVHEGIQTYFVQFKDDAEKYSKNKVWEVHAGGQVILCPTSVFGSDEVSSAEIIRQHLANHSAATHTKTVALGTKETQTTIQRPRSEPDTGNPCHTNKLLHRDSVDSAPILTAVNSSHKGRINCNSNTTPIVHLKGDANTLKCLRYRFKKHCKLYTAVSSTWHWTGHNVKHKSAIVTLTYDSECQREQFLSQVKIPKTITVSTGFMSI
····································································ALQAIELQL(A*0201)························································································································································································································································································
····························································································TLQDVSLEV(A*0201)································································································································································································································································
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·····························································································································································································································································································································································KIPKTITVSTGFMSI(DR1)