HPV16 E2

Accession: H001927

Uniprot: G0XRL2

Protein: E2

Organism: Human papillomavirus type 16

Function

It is responsible for recognition and binding of origin of replication. It exists in two forms such as full length (transcriptional transactivator) and truncated (transcriptional repressor). The ratio of these found in the heterotrimeric complex, formed b

Sequence&Mutation

         .         .         .         .         .         .
AGGQVILCPT VFSSNEVSS EIIRQHLAN PAATKTKAG LGTEEKQTT QRPRSEPDT
         .         .         .         .         .         .
GNPCHTTKLL RDSVDSAPI TAFNSSHKG INCNSNTTP VHLKGDANT KCLKYRFKK
         .         .         .         .         .          
HCTLYTAVSS WHWTGHNVK KSAIVTLTY SEWKRDQFL QVKIPKTIT STGFMSI

Epitope&Mutation

>H001927_E2
AGGQVILCPTSVFSSNEVSSPEIIRQHLANHPAATKTKAGALGTEEKQTTIQRPRSEPDTGNPCHTTKLLHRDSVDSAPILTAFNSSHKGRINCNSNTTPIVHLKGDANTLKCLKYRFKKHCTLYTAVSSTWHWTGHNVKHKSAIVTLTYDSEWKRDQFLSQVKIPKTITVSTGFMSI
···················································································FNSSHKGRINCNSNTTPIVHLKGDANTLKC(DR)·····························································
···················································································FNSSHKGRINCNSNTTPIVHLKGDANTLKC(DR1)····························································
···················································································FNSSHKGRINCNSNTTPIVHLKGDANTLKC(DR2)····························································
···················································································FNSSHKGRINCNSNTTPIVHLKGDANTLKC(DR3)····························································
···························································································································LYTAVSSTWHWTGHN(DQ6)···································
································································································································SSTWHWTGHNVKHKS(DRB1*1502)························
······························································································································································FLSQVKIPKT(DR15)····
··································································································································································KIPKTITVSTGFMSI(DR1)