HPV16 E2

Accession: H001923

Uniprot: I1SV05

Protein: E2

Organism: Human papillomavirus type 16

Function

It is responsible for recognition and binding of origin of replication. It exists in two forms such as full length (transcriptional transactivator) and truncated (transcriptional repressor). The ratio of these found in the heterotrimeric complex, formed b

Sequence&Mutation

         .         .         .         .         .         .
METLCQRLNV QDKILTHYE DSTDLREHI YWKHMRLEC IYYKAREMG KHINHQVVP
         .         .         .         .         .         .
TLAVSKNKAL SIELQLTLE IYNSQYSNE WTLQDVSLE YLTAPTGCI KHGYTVEVQ
         .         .         .         .         .         .
FDGDICHTMH ANWTHIYIC EASVTVVEG VDYYGLYYV EGIRTYFVQ KDDAEKYSK
         .         .                                        
NKVWEVHAGG VILCPTSVF SNE   

Epitope&Mutation

>H001923_E2
METLCQRLNVCQDKILTHYENDSTDLREHIDYWKHMRLECAIYYKAREMGFKHINHQVVPTLAVSKNKALQSIELQLTLETIYNSQYSNEKWTLQDVSLEVYLTAPTGCIKKHGYTVEVQFDGDICHTMHYANWTHIYICEEASVTVVEGQVDYYGLYYVHEGIRTYFVQFKDDAEKYSKNKVWEVHAGGQVILCPTSVFSSNE
····························································································TLQDVSLEV(A*0201)·······························································································
·········································································································································YICEEASVTV(A*0201)·················································