HPV16 E1

Accession: H001908

Uniprot: C6K5X4

Protein: E1

Organism: Human papillomavirus type 16

Function

ATP-dependent DNA helicase required for initiation of viral DNA replication. It forms a complex with the viral E2 protein.

Sequence&Mutation

         .         .         .         .         .         .
QQMLQVEGRH TETPCSQYS GSGGGCSQY SGSGGEGVS RHTTCQTPL NILNVLKTS
         .         .         .         .         .         .
NAKAAMLAKF ELYGVSFSE VRPFKSNKS CCDWCIAAF LTPSIADSI TLLQQYCLY
         .         .         .         .         .         .
LHIQSLACSW MVVLLLVRY CGKNRETIE LLSKLLCVS MCMMIEPPK RSTAAALYW
         .         .         .         .                    
YKTSISNISE YGDTPEWIQ QTVLQHSFN CTFELSQMV WAFDK 

Epitope&Mutation

>H001908_E1
QQMLQVEGRHETETPCSQYSGGSGGGCSQYSSGSGGEGVSERHTTCQTPLTNILNVLKTSNAKAAMLAKFKELYGVSFSELVRPFKSNKSTCCDWCIAAFGLTPSIADSIKTLLQQYCLYLHIQSLACSWGMVVLLLVRYKCGKNRETIEKLLSKLLCVSPMCMMIEPPKLRSTAAALYWYKTSISNISEVYGDTPEWIQRQTVLQHSFNDCTFELSQMVQWAFDK
···············································································································TLLQQYCLYL(A*0201)·································································································
················································································································LLQQYCLYL(A2)·····································································································