HPV16 E2

Accession: H001899
Uniprot: I3NN84
Protein: E2
Organism: Human papillomavirus type 16

Function

It is responsible for recognition and binding of origin of replication. It exists in two forms such as full length (transcriptional transactivator) and truncated (transcriptional repressor). The ratio of these found in the heterotrimeric complex, formed b

Sequence&Mutation

         .         .         .         .         .         .
MDSLCQRLNE QDKILTHYE DSTVLRDHI YWKQMRLEC IYYKAREIG KHINYQVVP
. . . . . .
TLAVSKNKTL AIELQLTLE IYNSQYSIE WTLQDVSLE YLTAPTGCI KHGFTVEMQ
. . . . . .
FDEDICSTMH TNWKYIYIC ETSVTVVEG VDYYGLYYV EGIRTYFVQ KDDAEKYSK
. .
NKVWEVHAGG VILCPTSVF SNE