HPV16 E2

Accession: H001863

Uniprot: I1SV08

Protein: E2

Organism: Human papillomavirus type 16

Function

It is responsible for recognition and binding of origin of replication. It exists in two forms such as full length (transcriptional transactivator) and truncated (transcriptional repressor). The ratio of these found in the heterotrimeric complex, formed b

Sequence&Mutation

         .         .         .         .         .         .
METLCQRLNV QDKILTHYE DSTDLRDHI YSKHMRLEC IYYKAREMG KHINHQVVP
         .         .         .         .         .         .
TLAVSKNKAL AIELQVTLE IYNSQYSNE WTLQDVSLE YLTAPTGCI KHGYTVEVQ
         .         .         .         .         .         .
FDGDICNTMH TNWTHIYIC EASVTVVEG VDYYGLYYV EGIRTYFVQ KDDAEKYSK
         .         .                                        
NKVWEVHAGG VILCPTSVF SNE   

Epitope&Mutation

>H001863_E2
METLCQRLNVCQDKILTHYENDSTDLRDHIDYSKHMRLECAIYYKAREMGFKHINHQVVPTLAVSKNKALQAIELQVTLETIYNSQYSNEQWTLQDVSLEVYLTAPTGCIKKHGYTVEVQFDGDICNTMHYTNWTHIYICEEASVTVVEGQVDYYGLYYVHEGIRTYFVQFKDDAEKYSKNKVWEVHAGGQVILCPTSVFSSNE
····························································································TLQDVSLEV(A*0201)·······························································································
·········································································································································YICEEASVTV(A*0201)·················································