HPV16 E2

Accession: H001852

Uniprot: Q07D06

Protein: E2

Organism: Human papillomavirus type 16

Function

It is responsible for recognition and binding of origin of replication. It exists in two forms such as full length (transcriptional transactivator) and truncated (transcriptional repressor). The ratio of these found in the heterotrimeric complex, formed b

Sequence&Mutation

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METLCQRLNV QDKILTHYE DSTDLRDHI YWKQMRLEC IYYKAREMG KHINHQVVP
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TLAVSKNKAL AIELQLTLE IYNSQYSNE WTLQDVSLE YLTAPTGCI KHGYTVEVQ
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FDGDICNTMH TNWKHIYIC DTSVTVVEG VDYYGIYYV EGIQTYFVQ KDDAEKYSK
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NKVWEVHAGG VILCPTSVF SDEVSSAEI RQHLANHSA THTKAVALG KETQTTIQR
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PRSELDTGNP HTNKLLHRD VDSAPILTA NSSHKGRIN NSNTTPIVH KGDANTLKC
         .         .         .         .         .         .
LRYRFKKHCK YTAVSSTWH TGHNVKHKS IVTLTYDSE QREQFLSQV IPKTITVST
                                                            
GFMSI     

Epitope&Mutation

>H001852_E2
METLCQRLNVCQDKILTHYENDSTDLRDHIDYWKQMRLECAIYYKAREMGFKHINHQVVPTLAVSKNKALQAIELQLTLETIYNSQYSNEKWTLQDVSLEVYLTAPTGCIKKHGYTVEVQFDGDICNTMHYTNWKHIYICEDTSVTVVEGQVDYYGIYYVHEGIQTYFVQFKDDAEKYSKNKVWEVHAGGQVILCPTSVFSSDEVSSAEITRQHLANHSAATHTKAVALGTKETQTTIQRPRSELDTGNPCHTNKLLHRDSVDSAPILTAVNSSHKGRINCNSNTTPIVHLKGDANTLKCLRYRFKKHCKLYTAVSSTWHWTGHNVKHKSAIVTLTYDSECQREQFLSQVKIPKTITVSTGFMSI
····································································ALQAIELQL(A*0201)························································································································································································································································································
····························································································TLQDVSLEV(A*0201)································································································································································································································································
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·····························································································································································································································································································································································KIPKTITVSTGFMSI(DR1)