HPV16 E2

Accession: H001831

Uniprot: I3NN83

Protein: E2

Organism: Human papillomavirus type 16

Function

It is responsible for recognition and binding of origin of replication. It exists in two forms such as full length (transcriptional transactivator) and truncated (transcriptional repressor). The ratio of these found in the heterotrimeric complex, formed b

Sequence&Mutation

         .         .         .         .         .         .
AGGQVILCPT VFSSNEVSS EIIMQHLVN SAATHTKAV SGTEETQTT QRPRSEPDT
         .         .         .         .         .         .
GNPCHTTKLL RDSVDSAPI TVFNSSHKG INCNSNTTP VHLKGDAIT KYLRYRFKK
         .         .         .         .         .          
HCTLYTAVSS WHWTGHNVK KSAIVTLTY SEWQRDQFL QVKISKTIT STGFMSI

Epitope&Mutation

>H001831_E2
AGGQVILCPTSVFSSNEVSSPEIIMQHLVNHSAATHTKAVASGTEETQTTIQRPRSEPDTGNPCHTTKLLHRDSVDSAPILTVFNSSHKGRINCNSNTTPIVHLKGDAITLKYLRYRFKKHCTLYTAVSSTWHWTGHNVKHKSAIVTLTYDSEWQRDQFLSQVKISKTITVSTGFMSI
·················································································································LRYRFKKHCTLYTAVSSTWHWTGHNVKHKS(DR)·······························
·················································································································LRYRFKKHCTLYTAVSSTWHWTGHNVKHKS(DR1)······························
·················································································································LRYRFKKHCTLYTAVSSTWHWTGHNVKHKS(DR2)······························
·················································································································LRYRFKKHCTLYTAVSSTWHWTGHNVKHKS(DR4)······························
···························································································································LYTAVSSTWHWTGHN(DQ6)···································
································································································································SSTWHWTGHNVKHKS(DRB1*1502)························
································································································································SSTWHWTGHNVKHKSAIVTLTYDSEWQRDQ(DR)················
································································································································SSTWHWTGHNVKHKSAIVTLTYDSEWQRDQ(DR1)···············
································································································································SSTWHWTGHNVKHKSAIVTLTYDSEWQRDQ(DR2)···············
································································································································SSTWHWTGHNVKHKSAIVTLTYDSEWQRDQ(DR3)···············