HPV16 E2

Accession: H001805

Uniprot: B9UPB8

Protein: E2

Organism: Human papillomavirus type 16

Function

It is responsible for recognition and binding of origin of replication. It exists in two forms such as full length (transcriptional transactivator) and truncated (transcriptional repressor). The ratio of these found in the heterotrimeric complex, formed b

Sequence&Mutation

         .         .         .         .         .         .
METLCQRLNV QDKILTHYE DSTDLRDHI YWKHMRLEC IYYKAREMG KHINHQVVP
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TLAVSKNKAL AIELQLTLE IYNSQYSNE WTLQDVSLE YLTTPTGCI KHGYTVEVQ
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FDGDICNTMH TNWKHIYIC EASVTVVEG VDYYGLYYV EGIRTYFVQ KDDAEKYSK
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NKVWEVHAGG VILCPTSVF SNEVSSPET RQHLANHSA THTKAVALG EETQTTIQR
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PRSEPDTGNP HTTKLLHRD VDSAPILTA NSSHKGRIN NSNTTPIVH KGDANTLKC
         .         .         .         .         .         .
LRYRFKKHCK YTAVSSTWH TGHNVKHKS IVTLTYDSE QRDQFLSQV IPKTITVST
                                                            
VFMSI     

Epitope&Mutation

>H001805_E2
METLCQRLNVCQDKILTHYENDSTDLRDHIDYWKHMRLECAIYYKAREMGFKHINHQVVPTLAVSKNKALQAIELQLTLETIYNSQYSNEKWTLQDVSLEVYLTTPTGCIKKHGYTVEVQFDGDICNTMHYTNWKHIYICEEASVTVVEGQVDYYGLYYVHEGIRTYFVQFKDDAEKYSKNKVWEVHAGGQVILCPTSVFSSNEVSSPETIRQHLANHSAATHTKAVALGTEETQTTIQRPRSEPDTGNPCHTTKLLHRDSVDSAPILTAFNSSHKGRINCNSNTTPIVHLKGDANTLKCLRYRFKKHCKLYTAVSSTWHWTGHNVKHKSAIVTLTYDSEWQRDQFLSQVKIPKTITVSTVFMSI
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