HPV16 E1

Accession: H001790

Uniprot: C6K5V1

Protein: E1

Organism: Human papillomavirus type 16

Function

ATP-dependent DNA helicase required for initiation of viral DNA replication. It forms a complex with the viral E2 protein.

Sequence&Mutation

         .         .         .         .         .         .
SVISGCVDNN SPRLKAICI KQSRAAKRR FESEDSGYG TEVETQQML VEGRHETET
         .         .         .         .         .         .
PCSQYSGGSG GCSQYSSGS GEGVSERHT CQTPLTNIL VLKTSNAKA MLAKFKELY
         .         .         .         .         .         .
GVSFSELVRP KSNKSTCCD CIAAFGLTP IADSIKTLL QYCLYLHIQ LACSWGMVV
         .         .         .         .         .         .
LLLVRYKCGK RETIEKLLS LLCVSPMCM IEPPKLRST AALYWYKTG SNISEVYGD
         .         .         .                              
TPEWIQRQTV QHSFNDCTF LSQMEQWAY N  

Epitope&Mutation

>H001790_E1
SVISGCVDNNISPRLKAICIEKQSRAAKRRLFESEDSGYGNTEVETQQMLQVEGRHETETPCSQYSGGSGGGCSQYSSGSGGEGVSERHTICQTPLTNILNVLKTSNAKAAMLAKFKELYGVSFSELVRPFKSNKSTCCDWCIAAFGLTPSIADSIKTLLQQYCLYLHIQSLACSWGMVVLLLVRYKCGKNRETIEKLLSKLLCVSPMCMMIEPPKLRSTAAALYWYKTGMSNISEVYGDTPEWIQRQTVLQHSFNDCTFELSQMEQWAYDN
·····························································································································································TLLQQYCLYL(A*0201)·································································································
······························································································································································LLQQYCLYL(A2)·····································································································