HPV16 E2

Accession: H001779

Uniprot: J3SRQ5

Protein: E2

Organism: Human papillomavirus type 16

Function

It is responsible for recognition and binding of origin of replication. It exists in two forms such as full length (transcriptional transactivator) and truncated (transcriptional repressor). The ratio of these found in the heterotrimeric complex, formed b

Sequence&Mutation

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METLCQRLNV QDKILTHYE DSTDLRDHI YWKQMRLEC IYYKAREMG KHINHQVVP
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TLAVSKNKAL AIELQLTLE IYNSQYSNE WTLQDVSLE YLTAPTGCI KHGYTVEVQ
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FDGDICNTMH TNWKYIYIC ETSVTVVEG VDYYGMYYV EGIQTYFVQ KDDAEKYSK
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NKVWEVHAGG VILCPTSVF SDEVSSAEI RQHLANHSA THTKAVALG KETQTTIQR
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PRSEPDTGNP HTNKLLHRD MDSAPILTA NSSHKGRIN NSNTTPIVH KGDANTLKC
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LRYRFKKHCK YTAVSSTWQ TGHNVKHKS IVTLTYDSE QREQFLSQV IPKTITVST
                                                            
GFMSI     

Epitope&Mutation

>H001779_E2
METLCQRLNVCQDKILTHYENDSTDLRDHIDYWKQMRLECAIYYKAREMGFKHINHQVVPTLAVSKNKALQAIELQLTLETIYNSQYSNEKWTLQDVSLEVYLTAPTGCIKKHGYTVEVQFDGDICNTMHYTNWKYIYICEETSVTVVEGQVDYYGMYYVHEGIQTYFVQFKDDAEKYSKNKVWEVHAGGQVILCPTSVFSSDEVSSAEIIRQHLANHSATTHTKAVALGTKETQTTIQRPRSEPDTGNPCHTNKLLHRDSMDSAPILTAVNSSHKGRINCNSNTTPIVHLKGDANTLKCLRYRFKKHCKLYTAVSSTWQWTGHNVKHKSAIVTLTYDSECQREQFLSQVKIPKTITVSTGFMSI
····································································ALQAIELQL(A*0201)························································································································································································································································································
····························································································TLQDVSLEV(A*0201)································································································································································································································································
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·····························································································································································································································································································································································KIPKTITVSTGFMSI(DR1)