HPV16 L1

Accession: H001741

Uniprot: F5CK01

Protein: L1

Organism: Human papillomavirus type 16

Function

Major capsid protein. It can form virus-like particles. It forms the pentameric assembly unit of the viral shell.

Sequence&Mutation

         .         .         .         .         .         .
TDEYVARTNI YHAGTSRLL VGHPYFPIK PNNNKILVP VSGLQYRVF IHLPDPNKF
         .         .         .         .         .         .
GFPDTSFYNP TQRLVWACV VEVGRGQPL VGISGHPLL KLDDTENAS YAANAGVDN
         .         .         .         .         .         .
RECISMDYKQ QLCLIGCKP IGEHWGKGS CTNVAVNPG CPPLELINT IQDGDMVDT
         .         .         .         .         .         .
GFGAMDFTTL ANKSEVPLD CTSICKYPD IKMVSEPYG SLFFYLRRK MFVRHLFNR
         .         .         .         .         .         .
AGAVGENVPD LYIKGSGST NLASSNYFP PSGSMVTSD QIFNKPYWL RAQGHNNGI
         .         .         .         .         .         .
CWGNQLFVTV DTTRSTNMS CAAISTSET YKNTNFKEY RHGEEYDLQ IFQLCKITL
         .         .         .         .         .         .
TADVMTYIHS NSTILEDWN GLQPPPGGT EDTYRFVTS AIACQKHTP APKEDPLKK
         .                                                  
YTFWEVNLKE FSADLDQF    

Epitope&Mutation

>H001741_L1
TDEYVARTNIYYHAGTSRLLAVGHPYFPIKKPNNNKILVPKVSGLQYRVFRIHLPDPNKFGFPDTSFYNPDTQRLVWACVGVEVGRGQPLGVGISGHPLLNKLDDTENASAYAANAGVDNRECISMDYKQTQLCLIGCKPPIGEHWGKGSPCTNVAVNPGDCPPLELINTVIQDGDMVDTGFGAMDFTTLQANKSEVPLDICTSICKYPDYIKMVSEPYGDSLFFYLRRKQMFVRHLFNRAGAVGENVPDDLYIKGSGSTANLASSNYFPTPSGSMVTSDAQIFNKPYWLQRAQGHNNGICWGNQLFVTVVDTTRSTNMSLCAAISTSETTYKNTNFKEYLRHGEEYDLQFIFQLCKITLTADVMTYIHSMNSTILEDWNFGLQPPPGGTLEDTYRFVTSQAIACQKHTPPAPKEDPLKKYTFWEVNLKEKFSADLDQF
·········································VSGLQYRVFRIHLPDP(DRB1*03)·····················································································································································································································································································································································································
···········································································································································································································································································································ICWGNQLFV(A*0201)···························································································································
···············································································································································································································································································································································································IHSMNSTIL(B*3901)·······················································
···································································································································································································································································································································································································································KYTFWEVNL(A24)······
····································································································································································································································································································································································································································YTFWEVNLK(A11)·····