HPV16 E2

Accession: H001740

Uniprot: I3NN82

Protein: E2

Organism: Human papillomavirus type 16

Function

It is responsible for recognition and binding of origin of replication. It exists in two forms such as full length (transcriptional transactivator) and truncated (transcriptional repressor). The ratio of these found in the heterotrimeric complex, formed b

Sequence&Mutation

         .         .         .         .         .         .
METLCQRLNV QDKILTHYE DSTDLRDHI YWKYMRLVC IYYKARELG KHINHQVVP
         .         .         .         .         .         .
TLAVSKNKAL AIELQLTLE IYNSQYSNE WTLQDVSLE YLTAPTGCI KHGYTVEVQ
         .         .         .         .         .         .
FDGDICNTMH INWTHIYIC EASVTVVEG VDYYGLYYV EGIRTYFVQ KDGAEKYSK
         .         .                                        
NKVWEVHAGG VILCPTSVF SNE   

Epitope&Mutation

>H001740_E2
METLCQRLNVCQDKILTHYENDSTDLRDHIDYWKYMRLVCAIYYKARELGFKHINHQVVPTLAVSKNKALQAIELQLTLETIYNSQYSNEKWTLQDVSLEVYLTAPTGCIKKHGYTVEVQFDGDICNTMHYINWTHIYICEEASVTVVEGQVDYYGLYYVHEGIRTYFVQFKDGAEKYSKNKVWEVHAGGQVILCPTSVFSSNE
····································································ALQAIELQL(A*0201)·······················································································································
····························································································TLQDVSLEV(A*0201)·······························································································
·········································································································································YICEEASVTV(A*0201)·················································