HPV16 E2

Accession: H001737

Uniprot: G0XRK9

Protein: E2

Organism: Human papillomavirus type 16

Function

It is responsible for recognition and binding of origin of replication. It exists in two forms such as full length (transcriptional transactivator) and truncated (transcriptional repressor). The ratio of these found in the heterotrimeric complex, formed b

Sequence&Mutation

         .         .         .         .         .         .
METLCQRLNV QDKILTHYE DSTDLRDHI YWKHMRLEC IYYKAREMG KHINHQVVP
         .         .         .         .         .         .
TLAVSKNKAL AIELQLTLE IYNSQYSNE WTLQDVSLE YLTAPTGCI KHGYTVEVQ
         .         .         .         .         .         .
FDGDICNTMH TNWTHIYIC EASVTVVEG VDYYGLYYV EGIQTYFVQ KDDAKKYSK
         .         .                                        
NKVWEVHAGG VILCPTSVF SNE   

Epitope&Mutation

>H001737_E2
METLCQRLNVCQDKILTHYENDSTDLRDHIDYWKHMRLECAIYYKAREMGFKHINHQVVPTLAVSKNKALQAIELQLTLETIYNSQYSNEKWTLQDVSLEVYLTAPTGCIKKHGYTVEVQFDGDICNTMHYTNWTHIYICEEASVTVVEGQVDYYGLYYVHEGIQTYFVQFKDDAKKYSKNKVWEVHAGGQVILCPTSVFSSNE
····································································ALQAIELQL(A*0201)·······················································································································
····························································································TLQDVSLEV(A*0201)·······························································································
·········································································································································YICEEASVTV(A*0201)·················································