HPV16 E2

Accession: H001729

Uniprot: K4F2S9

Protein: E2

Organism: Human papillomavirus type 16

Function

It is responsible for recognition and binding of origin of replication. It exists in two forms such as full length (transcriptional transactivator) and truncated (transcriptional repressor). The ratio of these found in the heterotrimeric complex, formed b

Sequence&Mutation

         .         .         .         .         .         .
METLCQRLNV QDKILTHYE DSTNLRDHI YWKHMRLEC IYYKAREMG KHINHQVVP
         .         .         .         .         .         .
TLAVSKNKAL AIELQLTLE IYNSQYSNE WTLQDVSLE YLTAPTGCI KHGYTVEVQ
         .         .         .         .         .         .
FDGDICNTMH TNWKHIYIC EASVTVVEG VDYYGLYYV EGIQTYFVQ KDDAEKYSK
         .         .         .         .         .         .
NKVWEVHAGG VILCPTSVF SNEVSSPET RQHLANHSA GTKETQTTI RPRSEPDTG
         .         .         .         .         .         .
NPCHTTKLLH DSVDSAPIL AFNSSHKGR NCNSNTTPI HLKGDANTL CLRYRFKKH
         .         .         .         .         .          
CKLYTAVSST HWTGHNVKH SAIVTLTYD EWQREQFLS VKIPKTITV TGFMSI

Epitope&Mutation

>H001729_E2
METLCQRLNVCQDKILTHYENDSTNLRDHIDYWKHMRLECAIYYKAREMGFKHINHQVVPTLAVSKNKALQAIELQLTLETIYNSQYSNEKWTLQDVSLEVYLTAPTGCIKKHGYTVEVQFDGDICNTMHYTNWKHIYICEEASVTVVEGQVDYYGLYYVHEGIQTYFVQFKDDAEKYSKNKVWEVHAGGQVILCPTSVFSSNEVSSPETIRQHLANHSALGTKETQTTIQRPRSEPDTGNPCHTTKLLHRDSVDSAPILTAFNSSHKGRINCNSNTTPIVHLKGDANTLKCLRYRFKKHCKLYTAVSSTWHWTGHNVKHKSAIVTLTYDSEWQREQFLSQVKIPKTITVSTGFMSI
····································································ALQAIELQL(A*0201)················································································································································································································································································
····························································································TLQDVSLEV(A*0201)························································································································································································································································
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