HPV16 E2

Accession: H001721

Uniprot: I1SV06

Protein: E2

Organism: Human papillomavirus type 16

Function

It is responsible for recognition and binding of origin of replication. It exists in two forms such as full length (transcriptional transactivator) and truncated (transcriptional repressor). The ratio of these found in the heterotrimeric complex, formed b

Sequence&Mutation

         .         .         .         .         .         .
METLCQRLNV QDKILTHYE DSTDLRDHI YWKHMRLEC IYYKAREMG KHINHQVVP
         .         .         .         .         .         .
TLAVSKNKAL AIELQLTLE IYNSQYSNE WTLQDVSLE YLTAPTECI KHGYTVEVQ
         .         .         .         .         .         .
FDGDICNTMH TNWTHIYIC EASVTVVEG VDYYGLYYV EGIRTYFVQ KDDAEKYSK
         .         .                                        
NKVREVHAGG VILCPTSVF SNE   

Epitope&Mutation

>H001721_E2
METLCQRLNVCQDKILTHYENDSTDLRDHIDYWKHMRLECAIYYKAREMGFKHINHQVVPTLAVSKNKALQAIELQLTLETIYNSQYSNEKWTLQDVSLEVYLTAPTECIKKHGYTVEVQFDGDICNTMHYTNWTHIYICEEASVTVVEGQVDYYGLYYVHEGIRTYFVQFKDDAEKYSKNKVREVHAGGQVILCPTSVFSSNE
····································································ALQAIELQL(A*0201)·······················································································································
····························································································TLQDVSLEV(A*0201)·······························································································
·········································································································································YICEEASVTV(A*0201)·················································