HPV16 E1

Accession: H001676

Uniprot: C6K5X0

Protein: E1

Organism: Human papillomavirus type 16

Function

ATP-dependent DNA helicase required for initiation of viral DNA replication. It forms a complex with the viral E2 protein.

Sequence&Mutation

         .         .         .         .         .         .
QMLQVEGRHE ETPCSQYSG SGGGSSQYS GSGGEGVSE HTICETPLT ILNVLKTSN
         .         .         .         .         .         .
AKAAMLAKFK LYGVSFTEL RPFKSNKST CDWCIAAFG TPSIADSIK LLQQYCLYL
         .         .         .         .         .         .
HIQSLACSWG VVLLLVRYK GKNRETIEK MSKLLCVSP CMMIEPPKL STAAALYWY
         .         .         .         .                    
KTGMSNISEV GDTPEWIQR TVLQHSFND TFELSQMVQ AFDN 

Epitope&Mutation

>H001676_E1
QMLQVEGRHETETPCSQYSGGSGGGSSQYSSGSGGEGVSERHTICETPLTNILNVLKTSNAKAAMLAKFKELYGVSFTELVRPFKSNKSTCCDWCIAAFGLTPSIADSIKTLLQQYCLYLHIQSLACSWGMVVLLLVRYKCGKNRETIEKLMSKLLCVSPMCMMIEPPKLRSTAAALYWYKTGMSNISEVYGDTPEWIQRQTVLQHSFNDCTFELSQMVQWAFDN
··············································································································TLLQQYCLYL(A*0201)·································································································
···············································································································LLQQYCLYL(A2)·····································································································