HPV16 E2

Accession: H001625

Uniprot: Q918U5

Protein: E2

Organism: Human papillomavirus type 16

Function

It is responsible for recognition and binding of origin of replication. It exists in two forms such as full length (transcriptional transactivator) and truncated (transcriptional repressor). The ratio of these found in the heterotrimeric complex, formed b

Sequence&Mutation

         .         .         .         .         .         .
LCQRLNVCQD ILTHYENDS DLRDHIDYW HMRLECAIY KAREMGFKH NHQVVPTLA
         .         .         .         .         .         .
VSKNKALQAI LQLTLETIY SQYSNEKWT QDVSLEVYL APTGCIKKH YTVEVQFDG
         .         .         .         .         .         .
DICNTMHYTN THIYICEEA VTVVEGQVD YGLYYVHEG RTYFVQFKD AEKYSKNKV
         .         .         .         .         .         .
WEVHAGGQVI CPTSVFSSN VSSPEIIRQ LANHPAATH KAVALGTEE QTTIQRPRS
         .         .         .         .         .         .
EPDTGNPCHT KLLHRDSVD APILTAFNS HKGRINCNS TTPIVHLKG ANTLKCLRY
         .         .         .         .         .         .
RFKKHCTLYT VSSTWHWTG NVKHKSAIV LTYDSEWQR QFLFQVKIP TITVSTGFM
                                                            
S     

Epitope&Mutation

>H001625_E2
LCQRLNVCQDKILTHYENDSTDLRDHIDYWKHMRLECAIYYKAREMGFKHINHQVVPTLAVSKNKALQAIELQLTLETIYNSQYSNEKWTLQDVSLEVYLTAPTGCIKKHGYTVEVQFDGDICNTMHYTNWTHIYICEEASVTVVEGQVDYYGLYYVHEGIRTYFVQFKDDAEKYSKNKVWEVHAGGQVILCPTSVFSSNEVSSPEIIRQHLANHPAATHTKAVALGTEETQTTIQRPRSEPDTGNPCHTTKLLHRDSVDSAPILTAFNSAHKGRINCNSNTTPIVHLKGDANTLKCLRYRFKKHCTLYTAVSSTWHWTGHNVKHKSAIVTLTYDSEWQRDQFLFQVKIPKTITVSTGFMS
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·························································································TLQDVSLEV(A*0201)·······························································································································································································································································
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