HPV18 E1
Accession: H001551
Uniprot: D3ITW5
Protein: E1
Organism: Human papillomavirus type 18
Function
ATP-dependent DNA helicase required for initiation of viral DNA replication. It forms a complex with the viral E2 protein.
Sequence&Mutation
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MADPEGTDGE TGCNGWFYV AIVDKKTGD ISDDEDENA DTGSDMVDF DTQGTFCEQ
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AELETAQALF AQEVHNDAQ LHVLKRKFA GSKENSPLG RLEVDTELS RLQEISLNS
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GQKKAKRRLF ISDSGYGCS VEATQIQVT NGEHGGNVC GGSTEAIDN GTEGNNSSV
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DGTSDNSNIE VNPHCTIAQ KDLLKVNNK GAMLAVFKD YGLSFTDLV NFKSDKTTC
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TDWVTAIFGV PTIAEGFKT IQPFILYAH QCLDCKWGV ILALLRYKC KSRLTVAKG
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LSTLLHVPET MLIQPPKLR SVAALYWYR GISNISEVM DTPEWIQRL IIQHGIDDS
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NFDLSEMVQW FDNELTDES MAFEYALLA SNSNAAAFL SNCQAKYLK CATMCKHYR
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RAQKRQMNMS WIRFRCSKI EGGDWRPIV FLRYQQIEF TFLGALKSF KGTPKKNCL
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VFCGPANTGK YFGMSFIHF QGAVISFVN TSHFWLEPL DTKVAMLDD TTTCWTYFD
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TYMRNALDGN ISIDRKHKP IQLKCPPIL TTNIHPAKD RWPYLESRI VFEFPNAFP
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FDKNGNPVYE NDKNWKCFF RTWSRLDLH EEEDADTEG PFGTFKCVA QNHRPL