HPV18 E7

Accession: H001526

Uniprot: D3ITV6

Protein: E7

Organism: Human papillomavirus type 18

Function

E7 protein is transforming protein. It binds to pRB/p107 and promotes its complete degradation.

Sequence&Mutation

         .         .         .         .         .         .
MHGPKATLQD VLHLEPQNE PVDLLCHEQ SDSEEENDE DGVNHQHLP RRAEPQRHT
         .         .         .         .                    
MLCMCCKCEA IELVVESSA DLGAFQQLF NTLSFVCPW ASQQ 

Epitope&Mutation

>H001526_E7
MHGPKATLQDIVLHLEPQNEIPVDLLCHEQLSDSEEENDEIDGVNHQHLPARRAEPQRHTMLCMCCKCEARIELVVESSADDLGAFQQLFLNTLSFVCPWCASQQ
MHGPKATLQDIVLHLEPQNEIPVDLLCHEQLS(DQ*0302)································································
MHGPKATLQDIVLHLEPQNEIPVDLLCHEQLS(DQ*0308)································································
MHGPKATLQDIVLHLEPQNEIP(DQ)···············································································
······TLQDIVLHL(A*0201)··················································································
····················IPVDLLCHEQLSDSEEENDEID(DQ*0302)······················································
·································SEEENDEIDGVNHQHLPARR(A*0201)············································
·····················································································FQQLFLNTL(A*0201)···
·······················································································QLFLNTLSFV(A2)····
·······················································································LFLNTLSFVCPWCASQQ(A*0201)
························································································LFLNTLSFV(A*0201)