HPV18 E7

Accession: H001524

Uniprot: Q9QNP5

Protein: E7

Organism: Human papillomavirus type 18

Function

E7 protein is transforming protein. It binds to pRB/p107 and promotes its complete degradation.

Sequence&Mutation

         .         .         .         .         .         .
MHGPKATLQD VLHLEPQNE PVGLLCHEQ SDSEEENDE DGVNHQHLP RRAEPQRHT
         .         .         .         .                    
MLCMCCKCEA IELVVESSA DLRAFQQLF KTLSFVCPW ASQQ 

Epitope&Mutation

>H001524_E7
MHGPKATLQDIVLHLEPQNEIPVGLLCHEQLSDSEEENDEIDGVNHQHLPARRAEPQRHTMLCMCCKCEARIELVVESSADDLRAFQQLFLKTLSFVCPWCASQQ
MHGPKATLQDIVLHLEPQNEIP(DQ)···············································································
······TLQDIVLHL(A*0201)··················································································
·································SEEENDEIDGVNHQHLPARR(A*0201)············································