HPV18 E7

Accession: H001504

Uniprot: Q9QNP7

Protein: E7

Organism: Human papillomavirus type 18

Function

E7 protein is transforming protein. It binds to pRB/p107 and promotes its complete degradation.

Sequence&Mutation

         .         .         .         .         .         .
MHGPKATLQD VLHLEPQNE PVDLLCHEQ SDSEEENDE DGVNHQHLP RRAEPQRHT
         .         .         .         .                    
MLCMCCKCEA IELVVESSA DLRAFQQLF KTLSFVCPW ASQQ 

Epitope&Mutation

>H001504_E7
MHGPKATLQDIVLHLEPQNEIPVDLLCHEQLSDSEEENDEIDGVNHQHLPARRAEPQRHTMLCMCCKCEARIELVVESSADDLRAFQQLFLKTLSFVCPWCASQQ
MHGPKATLQDIVLHLEPQNEIPVDLLCHEQLS(DQ*0302)································································
MHGPKATLQDIVLHLEPQNEIPVDLLCHEQLS(DQ*0308)································································
MHGPKATLQDIVLHLEPQNEIP(DQ)···············································································
······TLQDIVLHL(A*0201)··················································································
····················IPVDLLCHEQLSDSEEENDEID(DQ*0302)······················································
·································SEEENDEIDGVNHQHLPARR(A*0201)············································